A compound of triazole Derivative, its use, procedures to prepare,Pharmaceutical composition containing it and a compound useful as an intermediate for preparing Said Compound triazole derivative

摘要

A triazole derivative compound responding to formula I in which: R1 represents a (C2-C6) alkyl; a group - (CH2) nG where n varies from 0 to 5 and Gre represents a non-aromatic mono- or polycyclic hydrocarbon group in C3-C13 possibly substituted by one or more (C1-C3) alkyl in which the group-phenyl is optionally substituted by or several times hear a halogen, by a (C1-C3) alkyl or by a (C1-C3) alkoxy, a group - (CH2) nNR2R3 in which n represents an integer from 1 to 6 and R2 and R3 identical or different represent a (C1-C3) alkyl or constitute with the nitrogen atom to which they are attached a morpholino, piperidino, pyrrolidinyl opiperazinyl group; X1, X2,X3 or X4 each independently represent a hydrogen atom, dehalogen, a (C1-C6) alkyl, a (C1-C3) alkoxy or a trifluoromethyl; it is understood that a single one among X1, X2, X3 or X4 possibly represents a dehydrogen atom; R4 represents hydrogen, a- (CH2) nCOOR5 group in which n is as defined above and R5 represents a hydrogen atom, a (C1-C6) alkyl or a (C6-C10) aryl- (C1-C6) )I rent; a (C1-C6) alkyl; a group - (CH2) nOR5 or a group - (CH2) nR2R3 in which n, R2, R3 and R5 are as previously defined; a group - (CH2) n-tetrazolyl in which n is as defined above,Or R4 represents a deformed group of salts from an alkaline or alkaline metal; Y1, Y2 and Y3 are independent representatives,a hydrogen, a halogen, a (C1-C3) alkyl; a (C1-C3) alkoxy, a nitro, a cyano, (C1-C6) acylamino, carbamoyl, trifluoromethyl, a COOR6 Group in which R6 represents hydrogen, or (C1-C3) alkyl; or a desussales or solvatos. Procedures for preparing it, pharmaceutical composition containing it and a compound useful as an intermediate to prepare it