Crystalline forms of endo-2,3-dihydro-n- (8-methyl-8-azabicyclo 3.2.1 oct-3-yl) -2 - -oxo-1h-benzimidazole-1- monohydrate carboxamide and endo-3-ethyl-2,3-dihydro-n- (8-methyl-8-azabicyclo 3.2.1 oc t-3-yl) -2-oxo- monohydrate 1h-benzimidazole-1-carboxamide as 5-ht antagonists

摘要

Crystalline monohydrates of endo-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H-ben zimidazole-1-carboxamide hydrochloride and of endo-3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-ox o-1H-benzimidazole-1-carboxamide hydrochloride of formula CHEM (Compound 2a: R = H (Compound 2b: R = C2H5 the processes for their preparation and pharmaceutical compositions containing them. IMAGE