Purified form of streptogramins, use of a co-crystallized compound, process of preparing a purified form of streptogramin, purified component of group a of streptogramins, use of one or more minor components of group a of streptogramins, co-crystallized compounds and composition pharmaceutical

摘要

Purified form of streptogramins consisting of a combination of one or more components of the B group of streptogramins, of general formula: IMAGE in which A1 is a radical of general formula: IMAGE or IMAGE for which R' is H or OH and Y is H, a methylamino radical or a dimethylamino radical, R is an ethyl radical or when R' is H, R may also represent -CH3, and R1 and R2 are H, or alternatively, A1 is a radical of formula: IMAGE R is an isobutyl radical, and R1 is OH and R2 is -CH3, and of one or more minor components of the A group of streptogramins, of general formula: IMAGE in which R'' is H or a methyl or ethyl radical, in the form of a cocrystallisate, coprecipitate or a physical mixture of powders.