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Pharmaceutical tablet comprising amylose sustituìda as a matrix for sustained release of the drug contained in the tablet

机译:包含直链淀粉的基质作为持续释放片剂中所含药物的基质的药物片剂

摘要

b "pharmaceutical tablet comprising amylose substituu00ecda as a matrix for sustained release of the drug contained in the film" d .Pharmaceutical tablet for oral administration of sustained release of a compressed mixture of at least two dried powders including a powder of a pharmaceutical drug in a matrix of liberau00e7Will the drugs.The sustained release matrix is composed of amylose replaced prepared by reaction in a basic means.Amylose with an organic substituent having a reactive function that reacts with the hydroxy groups of the molecule of amylose.This substituent is preferably an epoxy or a halogen c16-18-alkane or alcohol with such a matrix controlled release and sustained a drug to be obtained with remarkable profile next to LiNear and long, 9 to 20 hours.
机译:“包含直链淀粉取代基作为基质的药物片剂,用于持续释放膜中所含药物。” d。用于口服给药的至少两种干燥粉末的压缩混合物的持续释放的药物片剂,包括药物的粉末在libera u7e的基质中。缓释基质由直链淀粉取代,该直链淀粉是通过碱性方法反应制得的。直链淀粉带有有机取代基,该取代基具有与羟基的羟基反应的反应性功能。该取代基优选是具有这样的基质控制释放并维持所要获得的药物的环氧或卤素的c16-18-烷烃或醇,其与LiNear相邻且持续9至20个小时很长。

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