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Nucleic acid construction for cell cycle regulated expression of structural genes.

机译：用于细胞周期的核酸构建调节结构基因的表达。

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摘要

Invention Patent: B "CONSTRUCTION OF NUCLEIC ACID FOR EXPRESSION REGULATED BY THE CELL CYCLE OF STRUCTURAL GENES" D. The invention relates to a nucleic acid construct comprising at least one activating sequence, at least one chimeric promoter module comprising a nucleotide sequence, which binds a protein from the E2F family and a protein from the CDF-1 family, and at least one structural gene, where said chimeric promoter module causes complete regulation of gene expression in the cell cycle later than the B-myb promoter, but earlier than the cdc25C promoter, and the CDF-1 protein.

机译：发明专利：“构建核酸以通过结构基因的细胞周期调节表达” 。本发明涉及一种核酸构建体，其包含至少一个激活序列，至少一个包含核苷酸序列的嵌合启动子模块，该核苷酸序列结合来自E2F家族的蛋白质和来自CDF-1家族的蛋白质，以及至少一个结构基因，其中所述嵌合启动子模块引起细胞周期中基因表达的完全调节，其晚于B-myb启动子，但早于cdc25C启动子和CDF-1蛋白。 展开▼

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公开/公告号BR9800641A

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公开/公告日1999-12-07

原文格式PDF

申请/专利权人 HOECHST AKTIENGESELLSCHAFT;
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申请/专利号BR19989800641

发明设计人 ROLF MUELLER;NINGSHU LIU;JOERK ZWICKER;HANS-HARALD SEDLACEK;
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申请日1998-02-17

分类号C07K14/47;C12N15/85;C12N15/12;A61K38/17;

国家 BR

入库时间 2022-08-22 01:57:18

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1. 用于结构基因的细胞周期调节表达的核酸构建体 [P] . 中国专利： CN1197077A . 1998-10-28

2. 核酸片段、含它的重组载体和其启动结构基因表达的方法 [P] . 中国专利： CN1198926C . 2005.04.27

3. Construction of nucleic acids for the expression of structural genes regulated by the cell cycle, these constructions of vector comprising a NucleicCell that includes the Construction of nucleic acid, Process for the preparation of such constructions and use of such [P] . AR011446A1 . 2000-08-16

机译：用于表达受细胞周期调控的结构基因表达的核酸的构建，这些包含核酸细胞的载体的构建包括核酸的构建，此类构建物的制备方法和此类核酸的用途

4. Nucleic acid construct for the cell cycle regulated expression of structural genes [P] . 美国专利： US6380170B1 . 2002-04-30

机译：用于细胞周期调控结构基因表达的核酸构建体

5. NUCLEIC ACID CONSTRUCTS FOR THE CELL CYCLE REGULATED EXPRESSION OF STRUCTURAL GENES [P] . HU9800329A3 . 2001-10-29

机译：核酸调控细胞结构基因表达的调控

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