An itraconazole exhibiting increased solubility, the method of preparation of it and the pharmaceutical composition for oral administration containing the same

摘要

B AN ITRACONAZOL SHOWING INCREASED SOLUBILITY, THE METHOD OF PREPARING THE SAME AND THE PHARMACEUTICAL COMPOSITION FOR ORAL ADMINISTRATION CONTAINING THE SAME D, in which the particle diameter of itraconazole, the insoluble drug, is thus reduced and crystalline, thus being transformed and crystalline crystalline in amorphic, increasing water solubility and dissolution rate. The improved itraconazole is a drug administered orally.