Use of one or more purified polypeptides or glycopeptides, derived from the protein and, preferably, ns1, ns3, or ns5, from different serotypes of flaviviridiae, notably dengue, diagnostic kit, and purified flaviviridiae specific antigen

摘要

"USE OF ONE OR VARIOUS PURIFIED POLYPEPTIMES OR GLYCOPEPTIDS FROM PROTEIN E, PRE M, NS ~ 1 ~, NS ~ 3 ~, or NS5, FROM DIFFERENT SOROTYPES OF FLAVIVIRIDIAE, NOTably FROM DENGUE, DIAGNOSTICALLY, PHYSICALLY, AND ANTIGENICALLY KIT. DE FLAVIVIRIDIAE ". The invention relates to the use of one or more polypeptides or glycopeptides from protein E, pre M, NS ~ 1 ~, NS ~ 3 ~ or NS ~ 5 ~, from different flaviviridiae serotypes, notably dengue, and having or not at its carboxyl end a residue of 2 to 8 amino acids, chosen from histidine, tryptophan or cysteine for the manufacture of a rapid diagnostic kit for the determination of the serotype incriminated in an infection by the dengue virus, and the primary or secondary nature of that specific infection of flaviviridiae comprising a possibly labeled polypeptide or glycopeptide from protein E, pre M, NS ~ 1 ~, NS ~ 3 ~ or NS ~ 5 ~, of a virus of the flaviviridiae family, and anti-IgG, anti- IgM or anti-IgA is either unmarked, marked or modified.