首页> 外国专利> Cyclohexyl and heterocyclic nucleoside derivatives, the method for producing such derivatives, and the use of derivatives and their oligomers or combined in pairing and/or testing systems

Cyclohexyl and heterocyclic nucleoside derivatives, the method for producing such derivatives, and the use of derivatives and their oligomers or combined in pairing and/or testing systems

机译:环己基和杂环核苷衍生物,生产此类衍生物的方法以及衍生物及其低聚物的用途或在配对和/或测试系统中的组合

摘要

Invention Patent: B "CYCLOHEXILA AND HETEROCICLILA NUCLEOSITY DERIVATIVES, METHOD FOR DERIVATIVE WASTE PRODUCTS, AND EMPLOYMENT OF DERIVATIVES AND THEIR OLIGHTS OR INJURIED UNDERTAKINGS AND/OR TEST SYSTEMS" D . This invention refers to a compound of formula (I),where: R^4^, ORO or SR with R and R^ 4^ being H or C~H~2n+1~,regardless of each other, and whether the same or different, n being an integer number of 1 to 12; 2 is equal to C~M~H~2m~C(X)-Y with X being =O, =S or =N; Y being equal to ORO,NRO^4^ or SR,where Rs and R^4^ having the same meaning given above, and m being a whole number of 1 to 4; or R2 is equal to C~m~H~2m~Z-Y'where Z being a group of sulfonyla, phosphonila, ether or amine, Y~ being equal to H, C~n~2n+1~,ONLY,NR R^4^or SR then Z is a sulphonyl or phosphonyl group, n, R^4 having the same meaning given above, and Y'being equal to C~N~H~2n+1 when Z is an ether group or an amine group; A, B and D are the same or different and mean CR^5^R^6^, NR O^7 or S, regardless of o n e, with R^5^5^5 R^6^and R^7 being H or C~H~2n+1, regardless of each other, having given meaning above; and C is equal to CR^8^ or N, with R^8^ having the meaning of R^5^ independently, A-B, B-C or C-D not being two heterogeneous atoms; and nucleobasis means timin, uracila, adenine, cytosine, guanine, isoguanine, isoguanine, isoguanine,xanthine or hypoxanthine. The invention also refers to a method for producing these derivatives and their jobs in pairing and/or testing systems.
机译:发明专利:“ B。环己基和杂核的核衍生物,衍生性废物产品的方法,以及衍生物和其轻质物质的使用或损害和/或试验系统的损害”。本发明涉及式(I)的化合物,其中:R ^ 4 ^,ORO或SR,其中R和R ^ 4 ^彼此为H或C〜H〜2n + 1〜,并且是否相同或不同,n为1至12的整数; 2等于C〜M〜H〜2m〜C(X)-Y,X为= O,= S或= N; Y等于ORO,NRO ^ 4 ^或SR,其中Rs和R ^ 4 ^具有与上文相同的含义,并且m为1-4的整数;或R2等于C〜m〜H〜2m〜Z-Y',其中Z是磺酰基,膦腈,醚或胺的基团,Y〜等于H,C〜n〜2n + 1〜,ON,NR R ^ 4 ^或SR,则Z为磺酰基或膦酰基,n,R ^ 4具有与上文相同的含义,并且当Z为醚基或Y时,Y'等于C〜N〜H〜2n + 1。胺基A,B和D相同或不同,均表示CR ^ 5 ^ R ^ 6 ^,NR O ^ 7或S,无论一个如何,其中R ^ 5 ^ 5 ^ 5 R ^ 6 ^和R ^ 7为H C〜H〜2n + 1,彼此无关,具有上述含义;或C等于CR ^ 8 ^或N,R ^ 8 ^独立地具有R ^ 5 ^的含义,A-B,B-C或C-D不是两个杂原子;核碱基是指timin,尿嘧啶,腺嘌呤,胞嘧啶,鸟嘌呤,异鸟嘌呤,异鸟嘌呤,异鸟嘌呤,黄嘌呤或次黄嘌呤。本发明还涉及在配对和/或测试系统中生产这些衍生物及其工作的方法。

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