'pharmaceutical preparation comprising clodronate as an active ingredient and microcrystalline cellulose as an excipient, manufacturing process and use of silicated microcrystalline cellulose in the manufacture of said pharmaceutical preparation'

摘要

"PHARMACEUTICAL PREPARATION UNDERSTANDING CHLODRONATE AS AN ACTIVE INGREDIENT AND MICROCRYSTALLINE CELLULOSE AS AN EXCIPIENT, MANUFACTURING PROCESS AND USE OF SILICATED MICROCRYSTALLINE CELLULOSE IN THE MANUFACTURE OF THAT PHARMACEUTICAL PREPARATION". The object of the present invention is a pharmaceutical preparation for oral use, especially a tablet, which as an active ingredient contains a pharmacologically acceptable salt of dichloromethylene bisphosphonic acid, that is, a clodronate, especially disodium clodronate and which, as an excipient, contains silicated microcrystalline cellulose . Other objects of the invention are a process for the manufacture of said pharmaceutical preparation and the use of silicated microcrystalline cellulose for the manufacture of said pharmaceutical preparation.