Nucleotide sequence, polypeptide, use of a polypeptide, processes of preparation of a polypeptide and of evidence or isolation of compounds capable of modulating or inhibiting the interaction between presenilins and polypeptides, host cell for the production of polypeptide, anti- oligonucleotide sense, nucleotide probe, antibody or antibody fragment, ligand of a polypeptide, use of a ligand, defective recombinant virus, vector, and pharmaceutical composition

摘要

"NUCLEOTHYDICAL SEQUENCE, POLYPEPTIDE, USE OF A POLYPEPTIDE, PROCEDURES FOR PREPARING A POLYPEPTIDE AND FOR THE EVIDENCE OR ISOLATION OF COMPOUNDS ABLE TO MODULAR OR INHIBIT THE INTERACTION BETWEEN THE PREVENTION AND THE POLYPOTHYLES - DIRECTION, NUCLEOTHYDIC PROBE, ANTIBODY OR ANTIBODY FRAGMENT, BINDER OF A POLYPEPTIDE, USE OF A BINDER, DEFECTIVE RECOMBINANT VIRUS, AND PHARMACEUTICAL COMPOSITION ". The present invention relates to new nucleotide and peptide sequences, and their pharmaceutical use. More particularly, the present invention relates to nucleic acids that encode proteins capable of interacting with presenilins.