首页> 外国专利> Enteric coated pharmaceutical dosage form, process for preparing it, using it, pellet or tablet fitted to it, and, processes to improve the inhibition of gastric acid secretion, and to improve the therapeutic effect in the treatment of associated gastrointestinal disorders with excess acid secretion

Enteric coated pharmaceutical dosage form, process for preparing it, using it, pellet or tablet fitted to it, and, processes to improve the inhibition of gastric acid secretion, and to improve the therapeutic effect in the treatment of associated gastrointestinal disorders with excess acid secretion

机译:肠溶衣药物剂型,其制备方法,使用它的方法,与之配套的丸剂或片剂,以及改善胃酸分泌抑制作用和改善治疗伴有过多酸分泌的胃肠道疾病的治疗方法

摘要

"ENTERED-COATED PHARMACEUTICAL DOSAGE FORM, PROCESS FOR THE PREPARATION OF THE SAME, USE OF THIS, PELLET OR TABLET ORDERED FOR THE SAME, AND, PROCESSES TO IMPROVE THE INHIBITION OF THE GERTRIC ACID SECRETATION, AND TO IMPROVE THE TREATMENT OF TREATMENT IN THE TREATMENT OF TREATMENT OF TREATMENT. ASSOCIATED WITH EXCESSIVE ACID SECRETATION ". Enteric coated pharmaceutical dosage form, comprising H ^ + ^, K ^ + ^ -ATPase inhibitor. The dosage form comprises at least two parts of the H ^ + ^, K ^ + ^ -ATPase inhibitor to be released in at least two consecutive pulses. The dosage form has at least one fraction with a delayed pulsed release and another fraction with instantaneous release of the H ^ + ^, K ^ + ^ -ATPase inhibitor. The parts are released in time in the range of 0.5 and up to 12 hours, preferably from 0.5 and up to 8 hours and more preferably from 0.5 and up to 4 hours apart. The dosage form is intended for administration once a day.
机译:“经包衣的药物剂型,制备相同制剂的过程,按相同用途订购的片剂,片剂或片剂的使用,以及改善抑制酸甘油酯分泌的过程,并改善对治疗的治疗治疗与酸分泌过多有关。”肠溶衣药物剂型,包含H ^ + ^,K ^ + ^ -ATPase抑制剂。该剂型包含至少两部分的H ^ + ^,K ^ + ^ -ATP酶抑制剂,以至少两个连续的脉冲释放。该剂型具有至少一个具有延迟脉冲释放的部分,以及具有瞬时释放的H ^ + ^,K ^ + ^ -ATPase抑制剂的另一部分。部件的时间间隔为0.5至12小时,优选0.5至8小时,更优选0.5至4小时。该剂型打算每天给药一次。

著录项

  • 公开/公告号BR9814389A

    专利类型

  • 公开/公告日2000-10-10

    原文格式PDF

  • 申请/专利权人 ASTRAZENECA AB;

    申请/专利号BR19989814389

  • 发明设计人 PER JOHAN LUNDBERG;BRITA SJOEBLOM;

    申请日1998-12-17

  • 分类号A61K9/26;A61K9/54;A61K31/44;A61K31/41;

  • 国家 BR

  • 入库时间 2022-08-22 01:57:06

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