Polymorph of 2- (3-cyano-4-isobutyl-oxy-phenyl) -4-methyl-5-thiazol-carboxylic acid, amorphous compound, processes for producing an amorphous compound, for crystal production, a, b, c, d, g of acid. 2- (3-cyano-4-isobutyl-oxy-phenyl) -4-methyl-5-thiazol-carboxylic, and polymorph

摘要

"ACID POLYMORPH 2- (3-CYAN-4-ISOBUTYL-OXY-PHENYL) -4-METHYL-5-THIAZOL-CARBOXYLIC, AMORPHUS COMPOUND, PROCESSES FOR THE PRODUCTION OF AN AMORPHY COMPOUND, FOR THE PRODUCTION OF CRYSTAL A, B, C, D, G OF 2- (3-CYANO-4-ISOBUTYL-OXY-PHENYL) -4-METHYL-5-THIAZOL-CARBOXYLIC ACID, E, POLYMORPH ". A process for preparing various polymorphic modifications of 2- (3-cyano-4-isobutyl-oxy-phenyl) -4-methyl-5-thiazol-carboxylic acid, each selectively by crystallization under the specific conditions determined by temperature and ratio of methanol / water from the mixed solvent to be used; and polymorphic modifications of 2- (3-cyano-4-isobutyl-oxy-phenyl) -4-methyl-5-thiazole-carboxylic acid as obtained by this process. A process of subjecting a specific polymorphic modification of the above acid to heating and vacuum drying to thereby obtain another polymorphic modification of the acid or an amorphous modification thereof; and polymorphic and amorphous modifications of the acid obtained by this process.