Proteìna fusion of main histocompatibility complex class II, in conjunction of the domìnios connection of main histocompatibility complex multimérico,Processes to detect T cells having a specificity o

摘要

"Proteu00ecna fusion of main histocompatibility complex class II, in conjunction of the domu00ecnios connection of main histocompatibility complex multimu00e9rico,Processes to detect T cells having a specificity of the complex set of MHC / peptu00ecdeo, to give a indivu00ecduo adoptive immunity to a complex set of MHC / peptu00ecdeo,To stimulate and activate T cells reactive to a complex set of MHC / peptu00ecdeo, to selectively kill T cells reactive to a complex set of MHC / peptu00ecdeo,For tolerizar a indivu00ecduo human to a complex set of MHC / peptu00ecdeo, and isolated nucleic acid ", the present invention is directed to the field of immunology.In particular, the present invention is directed into the planning, production and use of proteins and conjugates of fusion of the binding domain of major histocompatibility complex monovalent.Multivalent and multimu00e9rico.