Compounds (1 - Oxy pyridin-4-yl) - amide chinolin carboxylic acid - 5 -,Useful in the treatment of diseases that can be Modulated by inhibition of phosphodiesterase IV OR tumor necrosis factor or states associated with a function of phosphodiesterase IVAccumulation of eosinophils, or function.

摘要

N - Oxide of formula (i), wherein R1, R2, R3, R4 are as defined in the specification, and the pharmaceutically acceptable salts thereof, are useful as therapeutic agents,For the treatment of Disease States associated with Proteins that mediate cell activity, such as the treatment of inflammatory diseases.