Derivatives of 3 - (W - Benzoyl - piperidino) alkyl) - 4H - benzopiran - 4 - ona, Preparation Method, Pharmaceutical compositions, and Integrin inhibitors useful in the treatment of ThrombosisMyocardial infarction, coronary heart disease, arteriosclerosis, tumor, osteoporosis and rheumatoid arthritis.

摘要

The compounds of formula I wherein R1, R2, R3, R4, R5, R6, R7, R8, R11, Z,M and N have the meanings indicated in claim 1, and their salts, solvates and acceptable from the Physiological Point of viewCan be used as Integrin Inhibitors, in particular for the prophylaxis and Treatment of Circulatory System Diseases, thrombosis,Myocardial infarction, Coronary Heart diseases, arteriosclerosis, osteoporosisPathological processes that are maintained or spread by angiogenesis and tumour Therapy.