首页> 外国专利> Condensed indole derivatives, process of their preparation, pharmaceutical preparations in which they are comprised and use of these derivatives for preparing pharmaceutical preparations

Condensed indole derivatives, process of their preparation, pharmaceutical preparations in which they are comprised and use of these derivatives for preparing pharmaceutical preparations

机译:缩合吲哚衍生物,其制备方法,包含它们的药物制剂以及这些衍生物在制备药物制剂中的用途

摘要

In the present invention there are disclosed condensed indole derivatives of the general formula I, in which the individual symbols have specific meaning as well as pharmaceutically acceptable salts of those compounds. Said compounds are capable to antagonize 5-Hti4-receptors a therefore they can be used for treating some diseases of stomach and intestinal system, heart and vascular system and disorders of central neural system. In the present invention there are also claimed a process for preparing such substances, pharmaceutical preparations in which said substances are comprised as well as use of the indicated derivatives for preparing the pharmaceutical preparations.
机译:在本发明中,公开了通式I的稠合的吲哚衍生物,其中各个符号具有特定含义,以及这些化合物的药学上可接受的盐。所述化合物能够拮抗5-Hti4-受体,因此它们可以用于治疗某些胃和肠系统疾病,心脏和血管系统疾病以及中枢神经系统疾病。在本发明中,还要求保护一种制备此类物质的方法,包含所述物质的药物制剂以及指定的衍生物在制备药物制剂中的用途。

著录项

  • 公开/公告号CZ286194B6

    专利类型

  • 公开/公告日2000-02-16

    原文格式PDF

  • 申请/专利权人 SMITHKLINE BEECHAM P.L.C.;

    申请/专利号CZ19940002210

  • 发明设计人 GASTER LARAMIE MARY;WYMAN PAUL ADRIAN;

    申请日1993-03-10

  • 分类号C07D487/04;C07D498/04;C07D513/04;C07D471/04;C07D519/00;A61K31/445;A61K31/535;

  • 国家 CZ

  • 入库时间 2022-08-22 01:56:55

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