(+) - NORTSISAPRID, SUITABLE FOR THE TREATMENT OF VIOLATIONS MEDIATED BY 5-НТ3 AND 5-НТ4 (RECEPTORS)

摘要

The present invention relates to (+) - norcisapride of formula (I) and compounds (V), as well as their pharmaceutically acceptable acid addition salts, a method for preparing said compound and its use for preparing a medicine for treating disorders of the gastrointestinal tract, without affecting central nervous system. A method of treating disorders of the gastrointestinal tract is also proposed. The compounds of formula (V) in which the piperidine ring has an absolute configuration (3S, 4R) and PG is methyloxycarbonyl, ethyloxycarbonyl, tert-butyloxycarbonyl or phenylmethyl. The international application was published together with an international search report.