Production of soluble recombinant tripsinogenos analogues (X - 11238)

摘要

Trypsin and tripsinu00f3geno analogues produced in recombinant form, including Nucleic Acids encoding Trypsin and tripsinu00f3geno analogues.The present Invention tripsinu00f3geno analogues contain modifications in the sequence so that the leader of the tripsinu00f3geno tripsinu00f3geno cannot be segmented by Trypsin or semejant EnzymesIs to Trypsin. The present Invention also provides processes for producing recombinant tripsinu00f3geno analogues that can be activated later.