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SYNTHETIC PEPTIDES FOR THE TREATMENT OF MYASTHENIA GRAVIS.
SYNTHETIC PEPTIDES FOR THE TREATMENT OF MYASTHENIA GRAVIS.
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机译:合成肽治疗重症肌无力。
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摘要
Peptides having at least nine amino acid residues each including an amino acid sequence which corresponds to position p200-208 or p262-266 of the human acetylcholine receptor (alpha)-subunit, but differing therefrom by one or more amino acid substitutions, are disclosed. These peptides inhibit the proliferative response of human peripheral blood lymphocytes to the myasthogenic peptides p195-212 and p259-271 and are suitable for treatment of subjects afflicted with myasthenia gravis.
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