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DOUBLY VIRUS-INACTIVATED HUMAN BLOOD PLASMA, BLOOD PLASMA DERIVATIVES PRODUCED THEREFROM AND METHOD FOR THEIR PRODUCTION
DOUBLY VIRUS-INACTIVATED HUMAN BLOOD PLASMA, BLOOD PLASMA DERIVATIVES PRODUCED THEREFROM AND METHOD FOR THEIR PRODUCTION
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机译:双重病毒灭活的人类血浆,血液血浆衍生物制备及其制备方法
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摘要
The invention concerns a method of producing a virally safe therapeutic biological preparation from human plasma using a detergent and retaining at least 50 % of the biological activity, the detergent being removed at the end of the method. Non-ionic surfactants, whose molecular structure comprises a hydrophobic part consisting of a linear aliphatic chain of between 8 and 10 carbon atoms, are used as detergents. The detergent treatment can be followed by a heat treatment, optionally using conventional stabilizers.
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