PREPARATION OF 1S-1A,2B,3B,4A(S*)-4-7-1-(3-CHLORO-2-THIENYL) METHYLPROPYLAMINO-3H-IMIDAZO4,5-BPYRIDIN-3-YL-N-ETHYL-2,3-DIHYDROXYCYCLOPENTANECARBOXAMIDE AND ITS INTERMEDIATES

摘要

The invention [1S- [1α, 2b, 3b, 4a (S *)]] - 4- [7 - [[1- (3-chloro-2-thienyl) methyl] propyl] amino] -3H-imidazo [4 , 5-b] Pyridin-3-yl] -N-ethyl-2,3-dihydroxycyclopentanecarboxamide relates to a novel process for the preparation of imidazopyridine by modified cyclization, to processes for the preparation of its intermediates and to the intermediates themselves. The above compound is an antihypertensive and anchemic cardioprotective agent which acts on the heart and circulatory system. It can also be used as an anti-lipolysis agent that lowers plasma lipid levels, serum triglyceride levels, and plasma cholesterol levels. SHE