MORPHOLOGICALLY HOMOGENOUS BIMOCLOMOL, PROCESS FOR PRODUCING PURE POLIMORPH MODIFICATIONS AND PHARMACEUTICAL COMPOSITIONS CONTAINING POLIMORPH MODIFICATIONS AS ACTIVE COMPONENTS

摘要

Preparation of pure ~a or ~b Bimoclomol (N-[2-hydroxy-3-(1-piperidinil)-propoxy]-3-pyridin-carboximodoil-chloride (Z)-2-butene-dioate) is based on crystallisation of the pure form from alcohol.