USE OF 3,4-DIPHENYL CHROMANS FOR MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PROPHYLAXIS OF GYNAECOLOGICAL DISORDERS

摘要

The present invention provides novel uses of compounds of general formula (I) wherein R1, R4 and R5 are individually hydrogen, hydroxy, halogen, trifluoromethyl, lower alkyl, lower alkoxy or (tertiary amino)(lower alkoxy); and R2 and R3 are individually hydrogen or lower alkyl, or as a pharmaceutically acceptable salt thereof in combination with a pharmaceutically acceptable carrier for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of gynaecological disorders, including endometriosis, dysfunctional bleedings, endometrial cancer, polycystic ovarian syndrome and anovulatoric bleeding and furthermore for thinning of the endometrium.