首页>
外国专利>
USE OF NAALADASE INHIBITOR FOR MANUFACTURE OF PHARMACEUTICAL COMPOSITION FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS
USE OF NAALADASE INHIBITOR FOR MANUFACTURE OF PHARMACEUTICAL COMPOSITION FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS
展开▼
机译:使用纳拉达斯抑制剂制造药物组合物以治疗动物的谷氨酸盐异常并影响其神经活性
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention includes compositions and methods of treatment for glutamate abnormalities and associated nervous tissue insult in a animal by inhibition of NAALADase enzyme. Compositions include glutamate-derived hydroxyphosphinyl derivative compounds, acidic peptide analogs, phosphinic acid derivatives and mixtures thereof that inhibit NAALADase enzyme activity and their use for treating glutamate abnormalities such as created by global and focal ischemia.
展开▼