Tramadol multiple unit formulations comprising individual pellets of trmadol coated with one or more membrane layers for controlling release

摘要

Pharmaceutical multiple unit formulations contain identical or different individual retard pellets which consist of a starter material coated with tramadol or its physiologically tolerable salts, which is coated with one or more membrane layers for controlled release consisting of a substance selected from the groups of ethylcelluloses and shellacs; without the addition of a plasticiser acceptable, release retarding substance. The multiple unit formulations may be administered as capsules or tablets