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Polycarboxylic based cross-linked copolymers and pharmaceutical compositions comprising the co-polymer as an inert support or excipient

机译:基于聚羧酸的交联共聚物和包含该共聚物作为惰性载体或赋形剂的药物组合物

摘要

Cross-linked copolymers based on non cross-linked polycarboxylic polymers and a cross-linking agent comprising at least two amine functions. The copolymers comprise at least one polycarboxylic polysaccharide and at least one other non cross-linked polycarboxylic polymer which is not a polycarboxylic polysaccharide, and is preferably a polycarboxylic acrylic polymer. The cross-linking agent is chosen from diamines, natural or synthetic amino acids or polyamines. Also disclosed are pharmaceutical compositions containing the above copolymer as an inert support or excipient.
机译:基于非交联的多元羧酸聚合物和包含至少两个胺官能团的交联剂的交联共聚物。所述共聚物包含至少一种多元羧酸多糖和至少一种其他非交联的多元羧酸聚合物,所述多元醇不是多元羧酸多糖,并且优选为多元羧酸丙烯酸聚合物。交联剂选自二胺,天然或合成氨基酸或多胺。还公开了含有上述共聚物作为惰性载体或赋形剂的药物组合物。

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