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Some pirrocarboxianilidas clustered; a new class of ligands for Brain GABA receptors.

机译:一些pirrocarboxianilidas成簇;脑GABA受体的新型配体。

摘要

The invention includes a design structure: one or a non-toxic salt acceptable on the medicine. Where: W is substituted or unsubstituted phenyl; X is hydrogen, hydroxyl or lower hydrocarbon; t is hydrogen, halogen, hydroxyl, nitro, amino or tar; R3 is hydrogen or organic; R4 is hydrogen, or substituted or unsubstituted organic; R5 and R6 are organic and inorganic substitutes; n is 1, 2, 3, or 4. Their compounds are painful. The brain receptor of the target country or the target country that is highly preferred,The opposite antagonists or dying people are associated with brain helper receptors. These compounds are useful for the diagnosis and treatment of anxiety and epilepsy. Overdose benzodiazepine in pharmacies and enhance memory.
机译:本发明包括设计结构:药物上可接受的一种或无毒盐。其中:W是取代或未取代的苯基; X是氢,羟基或低级烃; t是氢,卤素,羟基,硝基,氨基或焦油; R3是氢或有机; R4是氢,或取代或未取代的有机基; R5和R6是有机和无机取代基; n为1、2、3或4。它们的化合物很痛苦。目标国家或目标国家的脑受体是高度优选的,相反的拮抗剂或垂死的人与脑辅助受体相关。这些化合物可用于诊断和治疗焦虑症和癫痫病。在药房中过量服用苯二氮卓类药物并增强记忆力。

著录项

  • 公开/公告号PA8434101A1

    专利类型

  • 公开/公告日2000-05-24

    原文格式PDF

  • 申请/专利权人 NEUROGEN CORPORATION;

    申请/专利号PA19978434101

  • 发明设计人 ALAN HUTCHINSON;PAMELA ALBAUGH;

    申请日1997-07-16

  • 分类号A61K31/03;C07D207/00;A61K31/44;C07D405/12;

  • 国家 PA

  • 入库时间 2022-08-22 01:55:25

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