首页> 外国专利> Azabicycle compounds replace isoaril aminoetal / benzisoxazol 5-HT1 as serum antibody positive

Azabicycle compounds replace isoaril aminoetal / benzisoxazol 5-HT1 as serum antibody positive

机译:Azabicycle化合物替代异烟尔氨基/苯并异恶唑5-HT1作为血清抗体阳性

摘要

The substance refers to azabicycle compound of isobutylene amine acyl / benzoisoxazol, wherein R1, R2, R3, R4 are h, C1-C4 tar, Alcoy C1-C4 (Alcoy C1-C4) is optionally changed to f; X is ch, N. preferred compound (7R, 9a) - trans - [2 - (5-fluoro-benzo [D] isoxal-3) - octabromo-1, - [2 - [2 - [2 - [2 - [2 - [2 -]]]]]]]]]]]]]]]] - IIz [1-methyl] - (5-fluoro-pyridine-2-il) amine,There are others He also mentioned a composer who included a 5-HT inhibitor, such as aspergillin. Compound I regulates serum reactive neurotransmitter 5-HT1, which can be used to treat hypertension, depression, general anxiety, phobia, post-traumatic stress syndrome, early ejaculation, obesity, headache and migration.
机译:该物质是指异丁烯基胺酰基/苯并异恶唑的氮杂双环化合物,其中R 1,R 2,R 3,R 4为h,C 1 -C 4焦油,Alcoy C 1 -C 4(Alcoy C 1 -C 4)任选地改变为f; X是ch,N。优选的化合物(7R,9a)-反式-[2-(5-氟-苯并[D]异草基-3]-八溴-1,-[2- [2-[2-[2-]]。 [2- [2- [2-]]]]]]]]]]]]]]]-IIz [1-甲基]-(5-氟吡啶-2-il)胺,还有其他他也提到作曲家包括5-HT抑制剂,例如曲霉吉林。化合物I调节血清反应性神经递质5-HT1,可用于治疗高血压,抑郁症,一般性焦虑症,恐惧症,创伤后应激综合征,早期射精,肥胖症,头痛和迁移。

著录项

  • 公开/公告号PE20001234A1

    专利类型

  • 公开/公告日2000-11-07

    原文格式PDF

  • 申请/专利权人 PFIZER PRODUCTS INC.;

    申请/专利号PE19990001116

  • 发明设计人 DESAI KISHOR AMRATLAL;BRIGHT GENE MICHAEL;

    申请日1999-11-04

  • 分类号C07D471/04;A61K31/505;

  • 国家 PE

  • 入库时间 2022-08-22 01:55:20

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