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METHOD OF OBTAINING NOVEL 2-24-(AMINOMETHYL)PHENYLPROPAN-2-OL AND THIS NOVEL COMPOUNDS AS SUCH AS WELL AS NOVEL INTERMEDIATE COMPOUNDS
METHOD OF OBTAINING NOVEL 2-24-(AMINOMETHYL)PHENYLPROPAN-2-OL AND THIS NOVEL COMPOUNDS AS SUCH AS WELL AS NOVEL INTERMEDIATE COMPOUNDS
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机译:获得新颖的2-2 [4-(氨基甲基)苯丙-2-醇和这种新颖化合物以及新颖的中间化合物的方法
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摘要
A process for preparing a compound of the formula IMG comprising reacting a compound of the formula IV with a carbonate base in an alcohol solvent. The compound of the formula IV is prepared by reacting a compound of the formula III with a methyl grignard reagent in an inert solvent. The compound of formula III is prepared by reacting a compound of formula II with an acetic anhydride and and amine base in a chlorinated solvent. The compound of Formula II is prepared by reacting a compound of forumula I with an alcohol in acid media to form an ester group. The invention also includes novel compounds of the formula IMG wherein R is (C1-C6)alkyl and IMG
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