首页> 外国专利> METHOD OF OBTAINING NOVEL 2-24-(AMINOMETHYL)PHENYLPROPAN-2-OL AND THIS NOVEL COMPOUNDS AS SUCH AS WELL AS NOVEL INTERMEDIATE COMPOUNDS

METHOD OF OBTAINING NOVEL 2-24-(AMINOMETHYL)PHENYLPROPAN-2-OL AND THIS NOVEL COMPOUNDS AS SUCH AS WELL AS NOVEL INTERMEDIATE COMPOUNDS

机译:获得新颖的2-2 [4-(氨基甲基)苯丙-2-醇和这种新颖化合物以及新颖的中间化合物的方法

摘要

A process for preparing a compound of the formula IMG comprising reacting a compound of the formula IV with a carbonate base in an alcohol solvent. The compound of the formula IV is prepared by reacting a compound of the formula III with a methyl grignard reagent in an inert solvent. The compound of formula III is prepared by reacting a compound of formula II with an acetic anhydride and and amine base in a chlorinated solvent. The compound of Formula II is prepared by reacting a compound of forumula I with an alcohol in acid media to form an ester group. The invention also includes novel compounds of the formula IMG wherein R is (C1-C6)alkyl and IMG
机译:制备式的化合物的方法,包括使式IV的化合物与碳酸酯碱在醇溶剂中反应。通过使式III的化合物与甲基格氏试剂在惰性溶剂中反应来制备式IV的化合物。通过使式II的化合物与乙酸酐和胺碱在氯化溶剂中反应来制备式III的化合物。通过使式I的化合物与醇在酸性介质中反应形成酯基来制备式II的化合物。本发明还包括式的新化合物,其中R是(C 1 -C 6)烷基和

著录项

  • 公开/公告号PL336111A1

    专利类型

  • 公开/公告日2000-04-25

    原文格式PDF

  • 申请/专利权人 PFIZER PRODUCTS INC.;

    申请/专利号PL19990336111

  • 发明设计人 MURRY JERRY ANTHONY;

    申请日1999-10-20

  • 分类号C07C215/68;C07C233/53;

  • 国家 PL

  • 入库时间 2022-08-22 01:55:16

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