N,O-SULFATED HEPAROSANES, PROCESS TO PRODUCE THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND ESCHERICHIA COLI (K5) SEBR 3282 STRAIN

摘要

N,O-Sulphated heparosans consisting of chains or of a mixture of chains with a molecular mass of between 1500 and 15000 Da, characterised by a repeated disaccharide structure of formula (I) in which - E denotes an acetyl group in 0 to 80 percent of the disaccharide units of the said N,O-sulphated heparosan, and a sulphate group and optionally a hydrogen atom in the remaining disaccharide units, - G denotes a hydrogen atom and a sulphate group, and the pharmaceutically acceptable salts of the said N, O-sulphated heparosans. Said heparosans can be utilised as medicaments.