Heterocyclic compounds as inhibitors of Enzymes rotamasa. Ref. PCs 9475 FEMA / BB.

摘要

The compounds of formula (i); in which a, y, r, X, R1, R2, R3 and R4 are as defined above are inhibitors of Enzymes rotamasa, particularly fkbp-12 and FKBP - 53.The compounds thus moderate regeneration and neuronal Growth and can be used for the treatment of Neurological Disorders that appear due to Neurodegenerative DiseasesS or other Disorders involving damage to the nerve.