首页>
外国专利>
Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells.
Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells.
展开▼
机译:具有平滑肌细胞和/或内皮细胞的组织嗜性的基因递送载体。
展开▼
页面导航
摘要
著录项
相似文献
摘要
The invention provides a nucleic acid delivery vehicle with or having been provided with at least a tissue tropism for smooth muscle cells and/or endothelial cells. In one aspect said nucleic acid delivery vehicle is a virus capsid or a functional part, derivative and/or analogue thereof. Preferably said virus capsid is an adnovirus capsid. Preferably said adenovirus is a subgroup B adenovirus, preferably adenovirus 16. Preferably said tissue tropism is provided by at least a tissue tropism determining part of an adenovirus fiber protein or a functional derivative and/or analogue thereof. The invention further presents methods for the treatment of diseases, preferably cardiovascular diseases.
展开▼