METHODS FOR DETECTING, PREVENTING, AND TREATING RENAL DISORDERS BY MODULATING, REGULATING, AND INHIBITING CONNECTIVE TISSUE GROWTH FACTOR

摘要

The present invention relates to methods for detecting, preventing, andtreating the progression of pathologies characterized by an accumulation ofthe extracellular matrix components by providing an agent to regulate,inhibit, or modulate the activity of Connective Tissue Growth Factor (CTGF).The method of the present invention is directed to treating kidney fibrosisand associated renal disorders, in particular, complications associated withdiabetes and hypertension.