AMPLIFICATION OF FOLATE-MEDIATED TARGETING TO TUMOR CELLS USING NANOPARTICLES

摘要

The invention relates to the delivery of drug, peptide and proteinpharmaceuticals using the folate-mediated uptake system. More particularly theinvention relates to the amplification of drug/pharmaceutical delivery withthe folate uptake system using a folate-nanoparticle complex. The inventionalso relates to processes for preparing the complexes, pharmaceuticalcompositions containing same, methods of treatment involving the complexes anduses of the complexes in the manufacture of medicaments.