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Multiple-container systems with improved sensitivity for optical analyses

机译:多容器系统,提高了光学分析的灵敏度

摘要

The invention relates to multiple-container systems and to the use of same for optical assays. The invention relates in particular to a multiple-container system comprising a container wall matrix (1) with continuous cavities and one or more optically transparent base plates (2) joined to the container wall matrix.aid system is characterized in that the base plates are coated with a film (3) having functional groups suitable for the covalent immobilization of molecules. The film on the base plate is preferably a Langmuir-Blodgett film, and preferably a Langmuir-Blodgett film on cellulose basis. The invention further relates to multiple-container systems comprising a container wall matrix with continuos cavities and one or more optically transparent base plates joined to the wall matrix. Said systems are characterized in that the base plates are coated with a film derivatized with receptor molecules or molecules presenting low non-specific protein adsorption.
机译:本发明涉及多容器系统及其在光学测定中的用途。本发明特别涉及一种多容器系统,其包括具有连续腔的容器壁基质(1)和连接至该容器壁基质的一个或多个光学透明基板(2)。该系统的特征在于,这些基板是用具有适于分子共价固定的官能团的膜(3)涂覆。基板上的膜优选为基于纤维素的Langmuir-Blodgett膜,并且优选为Langmuir-Blodgett膜。本发明进一步涉及一种多容器系统,其包括具有连续腔的容器壁矩阵和连接至该壁矩阵的一个或多个光学透明基板。所述系统的特征在于,基板涂覆有用受体分子或呈现低非特异性蛋白质吸附的分子衍生的膜。

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