A method for placing a photo-cross-linking agent at specific internal sites within the sequence of synthetic strands of ribonucleic acids

摘要

This invention describes novel photoactive ribonucleotides that contain photocrosslinking agents placed at specific internal positions within a ribonucleotide. The invention also provides methods for identifying novel, sequence-specific target molecules, using the photoactive ribonucleotides of the invention, as well as improved nucleic acid hybridization analysis methods.