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Polymorphisms in the human vcam-1 gene, suitable for diagnosis and treatment of vcam-1 ligand mediated diseases
Polymorphisms in the human vcam-1 gene, suitable for diagnosis and treatment of vcam-1 ligand mediated diseases
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机译:人类vcam-1基因的多态性,适用于vcam-1配体介导的疾病的诊断和治疗
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摘要
This invention relates to polymorphisms in the human Vascular Cell Adhesion Molecule-1 (VCAM-1) gene, in particular at one or more of positions 278, 647, 707, 748, 829 and 1467 in the VCAM-1 gene as defined by the positions in EMBL ACCESSION NO. M92431. The invention also relates to methods and materials for analysing allelic variation in the VCAM-1 gene, and to the use of VCAM-1 polymorphism in the diagnosis and treatment of VCAM-1 ligand mediated diseases such as multiple sclerosis, rheumatoid arthritis, atherosclerosis and allergic asthma.
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