METHOD FOR CONSTRUCTING LIBRARIES OF PHENOTYPIC PROFILES

摘要

Methods are provided for use in constructing libraries of phenotypic profiles in a nematode worm such as C. elegans. The methods require measurement of identifiable characteristics of the worm and systematic scoring of these characteristics. Also provided are methods of identifying compounds with potential pharmacological activity, for determining the mode of action of a given compound and for assigning genes to particular biochemical pathways.