INSTRUMENTATION AND METHOD FOR EVALUATING CLOT ELASTIC MODULUS, FORCE DEVELOPMENT AND ERYTHROCYTE FLEXIBILITY DURING CLOTTING AND DISSOLUTION

摘要

the application and removal of an intermittent compressive stress on a blood sample (8) positioned between a pair of plates (12, 14) for the duration of the formation and dissolution of clots, provide a reference for further use an output signal ion from a transducer (22) to determine the parameters of the resistance and elastic modulus.the development effort comes from the internal actions of platelets during clot retraction of. the elastic modulus is a measure of the stiffness of the clot. coagulation can be measured in the form of an increase in the elastic modulus of the work products and stone.the dissolution of the thrombus can be determined by a dramatic decrease of the elastic modulus and work products.if the blood sample has a solubilizing agent such as tpa clots, it is difficult to determine the whole blood fibrinolytic potential and to identify patients at risk of thrombosis as a result of a decrease in the ability of dissolution of cail lots. the elastic modulus of blood clots is a measure of flexibility.