SELECTION OF TARGETED CONTRAST AGENTS FROM A COMBINATORIAL LIBRARY

摘要

The invention provides a method for the selection of a candidate targeted contrast agent, comprising the steps of: (i) obtaining a library of vector: reporter conjugates in which conjugates where the vector is an oligomer (and optionally also where vectors are non-oligomeric) the conjugate contains a heterologous reporter; and (ii) testing the members of said library to identify a said member having a binding affinity for a biological target.