CHROMATOGRAPHIC SEPARATION PROCESS AND CHROMATOGRAPHIC SEPARATOR

摘要

PROBLEM TO BE SOLVED: To provide a method and an apparatus, for a chromatographic separation, in which at least a part of the ion shape of an ion exchanger at least in a part is changed in every process in a plurality of chromatographic separation processes and in which a fluid raw material containing three or more components can be separated efficiently into three or more compartments. ;SOLUTION: In a plurality of chromatographic separation processes which use a chromatographic separation apparatus which is filled with an ion exchanger, at least a part of the ion shape of the ion exchanger at least in a part in every process is changed into an ion shape which is suitable for separating a component to be separated. A fluid raw material F which contains three or more components is separated efficiently into three or more compartments A to C. In one preferable example for the chromatographic separation apparatus, a shutoff valve is provided in one position of a circulation flow passage in a unit filling layer group which forms an endless series circulation flow passage, fluid-raw-material supply means 1F to 10F, desorption- agent supply means 1D to 10D and two-compartment-portion pulling-out means 1A to 10A, 1C to 10C are provided, and a one-fluid-compartment-portion pulling-out means which is connected to the circulation flow passage is provided on the upstream side of the shutoff valve and without the intermediary of a unit filling layer.;COPYRIGHT: (C)1999,JPO