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ANTISENSE AND ANTIGENE THERAPEUTICS WITH IMPROVED BINDING PROPERTIES AND METHODS FOR THEIR USE
ANTISENSE AND ANTIGENE THERAPEUTICS WITH IMPROVED BINDING PROPERTIES AND METHODS FOR THEIR USE
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机译:具有改进的结合性能的抗敏和抗抗原治疗剂及其使用方法
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摘要
The present invention is directed to novel nucleic acid molecules and methods for their use. More specifically, the novel nucleic acid molecules of the present invention are capable of tightly and specifically interacting with a target molecule of interest not only through standard Watson-Crick base pairing, but also through additional features which allow the antisense molecules to become topologically "locked" onto the target nucleic acid, thereby imparting improved transcription and translation inhibitory properties.
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