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FACTOR G REDUCED AMEBOCYTE LYSATES FOR DETECTION OF BACTERIAL ENDOTOXINS
FACTOR G REDUCED AMEBOCYTE LYSATES FOR DETECTION OF BACTERIAL ENDOTOXINS
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机译:因子G还原的糖原裂解物用于细菌内毒素的检测
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摘要
The invention provides methods and compositions for the detection and/or quantification of bacterial endotoxins. In particular, provided herein is an inexpensive and reproducible method for producing an improved amebocyte lysate preparation having reduced Factor G activity. Provided also is an endotoxin-specific amebocyte lysate preparation produced by such a method. In addition, the invention provides methods and compositions for enhancing the sensitivity to endotoxins of amebocyte lysate preparations having reducing Factor G activity. In particular, the sensitivity of such amebocyte lysate preparations to endotoxins can be enhanced by the addition of exogenous (1→3) &bgr;-D-glucan.
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