USE OF GREEN PORPHYRINS IN THE MANUFACTURE OF A MEDICAMENT IN THE TREATMENT OF ATHEROSCLEROSIS WITHOUT PURPOSEFUL IRRADIATION OF THE PORPHYRIN DERIVATIVES

摘要

PURPOSE: A method for preventing or inhibiting the development of arterial plaque by administering an amount of a green porphyrin compound is provided which needs not be accompanied by any purposeful irradiation with light. CONSTITUTION: A method to prevent or inhibit the development of arterial plaque, comprising the steps of: (a) administering to a subject an amount of a green porphyrin compound effective to prevent or inhibit said development; and (b) allowing the inhibition to occur in the absence of irradiation with light absorbed by the green porphyrin; or a pharmaceutical composition for preventing or inhibiting the development of arterial plaque is described. The composition comprises: (a) an amount of a green porphyrin compound effective to prevent or inhibit the development when administered to a subject in need of such treatment, even in the absence of irradiation with light absorbed by said green porphyrin; and (b) a pharmaceutically acceptable excipient. The administration of the green porphyrin need not be accompanied by any purposeful irradiation with light.