COMPOSITION COMPRISING THE EXTRACT OF DRYNARIA FORTUNEI J. SM. FOR PROMOTING THE REGENERATION OF HARD TISSUES

摘要

Purpose: a pharmaceutical composition includes the extract of Mongolian oak fern J. It provides for promoting hard tissues, such as the generation Sm. of bone and tooth. Construction: pharmaceutical composition includes Mongolian oak fern J.The extract of Sm. The extract of Mongolian oak fern J. Sm.Repetitive routine is prepared by it to be formed by heating the 50-100% methanol aqueous solutions comprising Mongolian oak fern J. In the 5-24 hours Sm. of temperature of 50-120C, the solution of cooling 40-60C, filtering solution; Concentrate solution. The extract of Mongolian oak fern J. Sm.Also by repetitive routine by making 50-100% methanol aqueous solutions include that Mongolian oak fern J forms preparation. At room temperature or in 5-7 days Sm. of 4C points, filtering solution; Concentrate solution. Extract liquor is dry to one powder of acquisition. Composition includes the extract of Mongolian oak fern J. A kind of Sm. in the form of liquid or a powder. Therefore the effect of composition promotion osteoblastic proliferation and periodontal ligament fibroblasts in vitro and the activity for improving alkaline phosphatase, promote the regeneration and diffusion of hard tissues, therefore can be used for handling or preventing osteoporosis or periodontitis. Composition can be used for the form of a toothpaste or a gargle. Composition is equally used as an additive of the feed of the shell of a hatcher one egg of reinforcement.