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ORAL PREPARATION FORMULA CONTAINING S-(3-HYDROXYPROPYL)-L-CYSTEIN

机译:含S-(3-羟基丙基)-L-半胱氨酸的口服制剂

摘要

PURPOSE: A solid formulation containing S-(3-hydroxypropyl)-L-cystein for oral preparation which does not be decolorized after a long period of storage is provided by mixing with a vehicle of substantially, only starch or cyclodextrin. CONSTITUTION: An oral preparation formula comprises S -(3-hydroxypropyl)-L-cystein(HPCY) which is useful as an expectorant and a vehicle which substantially contains only starch, or cyclodextrin. The starch which can be used for this formulation includes corn starch, potato starch, wheat starch, rice starch and the mixtures thereof, and the cyclodextrin, for example, includes alpha-cyclodextrin, beta-cyclodextrin, gamma-cyclodextrin and the mixtures thereof. The used amount is not particularly limited, but starch or cyclodextrin is used 0.01-8parts by weight, and preferably 0.02-4 parts by weight, per 1 part by weight of HPCY.
机译:用途:通过与基本上仅淀粉或环糊精的赋形剂混合,提供用于口服制剂的包含S-(3-羟丙基)-L-半胱氨酸的固体制剂,其在长时间储存​​后不会脱色。组成:一种口服制剂,包含用作祛痰剂的S-(3-羟丙基)-L-半胱氨酸(HPCY)和基本上仅含有淀粉或环糊精的赋形剂。可用于该制剂的淀粉包括玉米淀粉,马铃薯淀粉,小麦淀粉,大米淀粉及其混合物,并且环糊精例如包括α-环糊精,β-环糊精,γ-环糊精及其混合物。用量没有特别限制,但是相对于每1重量份HPCY,淀粉或环糊精的用量为0.01〜8重量份,优选为0.0〜2重量份。

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