A THIAPENTARENE CARBOXYLATE DERIVATIVE AS NON-STEROID ANTI-INFLAMMATORY AGENT

摘要

The present invention is a novel nonsteroidal anti-inflammatory drug, the ester derivative of thiapentarenic carboxylic acid represented by the following general formula (I), in which gastrointestinal side effects are minimized, and a pharmaceutically acceptable salt thereof, a method for preparing the same, and the effectiveness of the compound It relates to a composition of anti-inflammatory analgesic containing a component.;Wherein R ₁ is phenyl or benzyl unsubstituted or substituted with halogen, R ₂ represents hydrogen, halogen or lower alkyl of 1 to 6 carbon atoms, R ₃ represents hydrogen, halogen, lower alkyl of 1 to 6 carbon atoms, Nitro, nitrooxy, cyano or substituted or unsubstituted amino groups, n being an integer from 0 to 6.