SYNTHETIC PEPTIDE, SYNTHETIC LIPOPEPTIDE, IMMUNOGENIC CONJUGATE (VARIANTS), METHOD OF OLIGOMER PREPARING, POLYSACCHARIDE PROTECTED BY SOLID POLYETHYLENE GLYCOL MONOMETHYL ESTER

摘要

FIELD: biotechnology, peptides. SUBSTANCE: invention relates to synthetic peptide showing an amino acid sequence relating to at least a single antigenic determinant of at least a single protein, usually structural protein, in part to proteins P1, P2 and P6 from Haemophilus influenzae (Hi), in part, of type B. Peptide is used as chimeric lipophilic form T-B attached to a carrier-molecule, for example, synthetic PRP-molecule and/or polymerized and forming molecular aggregates as vaccine against Hi. EFFECT: peptide indicated above, improved method of preparing. 35 cl, 28 dwg, 12 tbl, 20 ex