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Amphiphilic compounds slides off from amino acids or peptides, a method for their preparation and their use as a pharmaceutical composition administration

机译:两亲性化合物从氨基酸或肽中滑落,其制备方法及其在药物组合物中的用途

摘要

Amphiphilic derivatives of amino acids or peptides are provided, comprising a polyhydroxylated hydrophilic part derived from a sugar, from a polyol, from an aminopolyol or from an oligosaccharide, and at least one hydrophobic part derived from a hydrocarbon, fluorocarbon, or a mixed fluorocarbon/hydrocarbon, saturated or unsaturated, having from 5 to 20 carbon atoms, the hydrophobic part(s) being linked to the hydrophilic part by a junction bearing an amino acid or a peptide.
机译:提供了氨基酸或肽的两亲衍生物,其包含衍生自糖,衍生自多元醇,衍生自氨基多元醇或寡糖的多羟基化亲水部分,以及至少一个衍生自烃,碳氟化合物或混合碳氟化合物的疏水部分/具有5至20个碳原子的饱和或不饱和烃,疏水部分通过带有氨基酸或肽的连接点与亲水部分连接。

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