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OBTAINING VACCINES TO PREVENT PATHOGENIC EFFECTS ASSOCIATED WITH RETROVIRAL INFECTION
OBTAINING VACCINES TO PREVENT PATHOGENIC EFFECTS ASSOCIATED WITH RETROVIRAL INFECTION
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机译:获得疫苗以预防与逆转录病毒感染相关的病原学影响
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摘要
The invention provides a method of searching for and obtaining a vaccine against the pathogenic effects related to the infection of an animal or human host by a retrovirus that penetrates into a target cell of the host, and a vaccine obtained by the method are provided. The method includes preparing candidate vaccine agents based on a polypeptide comprising at least part of an envelope protein of a pathogenic strain of the retrovirus and selecting as the vaccine a modified polypeptide chosen from polypeptides that induces an immune response directed against an immunodominant region of an envelope protein of the retrovirus and not against a protein of the host.
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